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Pleomorphic adenomas which occured in the submandibular gland and hard palate : reports of two cases

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Abstract


Pleomorphic adenoma(benign mixed tumor) is the most common tumor of the major salivary glands, constituting approximately 70 per cent of benign tumors of these glands. The term mixed tumor was introduced in the nineteenth century to stress the
dual
origin of this neoplasm from epithelial and mesenchymal elements, and the designation pleomorphic adenoma is preferred because it emphasizes both the epithelial origin and the variety of histological patterns found in this common salivary gland
lesion.
Rauch, in a review of 4245 pleomorphic adenomas, found 92.5 per cent in the major salivary glands and 6.5 per cent in the minor salivary glands, 8 per cent arose in the submandibular glands, and in another large series of over 6,000 cases,
approximately
4 per cent arose in the hard and soft palates with equal frequency in each.
The prognosis of pleomorphic adenoma depends more upon the choice and adequacy of treatment than upon histological appearances. The accepted treatment for this tumor is surgical excision. With adequate surgery recurrence rates of less than 1 per
cent
can be obtained. In this hospital, I experienced two patients who were identified PMA which occured in the hard palate and submandibular gland. The lesions were successfully treated by surgery.

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